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Psychedelics U.S. states such as Oregon and Colorado have also instituted decriminalization and legalization measures of Psychedelic s and states like New Hampshire and others are attempting to do the same. Mescaline (3,4,5-trimethoxyphenethylamine) is a phenethylamine alkaloid found in various species of cacti, the most well known being Peyote and San Pedro . Mescaline has effects comparable to those of LSD and psilocybin, albeit with a greater emphasis on colors and patterns. Eligible participants had a primary DSM-IV diagnosis (adjustment disorder with anxiety and depressed mood, chronic; adjustment disorder with anxiety, chronic; and generalized anxiety disorder), with more than one-half of the participants in advanced stages of their illness. Participants were assigned to receive psilocybin (0.3 mg/kg) or niacin administered during two 8-hour treatment sessions. After a long hiatus in clinical research, one of the most exciting and encouraging recent developments in this field